OSMANLI SURİYE'SİNDE SUÇLAR (1880-1884)

Osmanli Devleti̇’ni̇n Kuruluş Ve Olgunlaşma Süreci̇

Tarih sahnesine bir uç beyliği olarak çıkan Osmanlıların kuruluş süreci, konuya ilişkin kaynakların yetersizliği veya bu kaynaklar arasındaki bazı çelişkili ifadeler yüzünden farklı yorumlara sebebiyet vermiştir.[1] Bu farklılıklar daha çok ‚kurucu çekirdek‛in mahiyeti üzerinde yoğunlaşmış olup Beyliği kuranların veya kuruluşta en önemli rolü oynayanların kabilevî bir topluluk mu, gaziler mi yo...

Dev118943 1879..1884

Chromobodies are intracellular nanoprobes that combine the specificity of antibodies with the convenience of live fluorescence imaging in a flexible, DNA-encoded reagent. Here, we present the first application of this technique to an intact living vertebrate organism. We generated zebrafish lines expressing chromobodies that trace the major cytoskeletal component actin and the cell cycle marker...

Dev105650 1884..1893

During morphogenesis, organs grow to stereotyped sizes, but growth control mechanisms are poorly understood. Here, we measured the signaling dynamics of the morphogen Dpp, one of several Drosophila factors controlling morphogenetic growth, in the developing eye. In this tissue, the Dpp expression domain advances from the posterior to the anterior tissue edge. In front of this moving morphogen s...

Quarter Ending 31st January 1884

Dmd058347 1873..1880

Historically, since the metabolism of administered peptide/protein drugs (“biotherapeutics”) has been expected to undergo predictable pathways similar to endogenous proteins, comprehensive biotherapeutic metabolism studies have not been widely reported in the literature. However, since biotherapeutics have rapidly evolved into an impressive array of eclectic modalities, there has been a shift t...